Gene Loss

Publication Details

Identifier: JB_QCAW4Q

Curator: M. Lopes-Marques

Title:

The Novel Evolution of the Sperm Whale Genome.

Abstract:

The sperm whale, made famous by Moby Dick, is one of the most fascinating of all ocean-dwelling species given their unique life history, novel physiological adaptations to hunting squid at extreme ocean depths, and their position as one of the earliest branching toothed whales (Odontoceti). We assembled the sperm whale (Physeter macrocephalus) genome and resequenced individuals from multiple ocean basins to identify new candidate genes for adaptation to an aquatic environment and infer demographic history. Genes crucial for skin integrity appeared to be particularly important in both the sperm whale and other cetaceans. We also find sperm whales experienced a steep population decline during the early Pleistocene epoch. These genomic data add new comparative insight into the evolution of whales.

Last update:

20-08-2024

Associated Glosses (19 results)

GlossID	Species	Symbol	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_0YBEXU	Physeter catodon	KLK8	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evx187
GL_276009	Physeter catodon	TMPRSS11B	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evx187
GL_4GNOS6	Physeter catodon	CPA2	Other	Full	No	10.1093/gbe/evx187
GL_8ND2IM	Physeter catodon	AMZ2	Other	Full	Physeter	10.1093/gbe/evx187
GL_BNJWYA	Physeter catodon	CASP12	Other	Full	No	10.1093/gbe/evx187
GL_E9ICEA	Physeter catodon	DPEP3	Other	Full	Physeter	10.1093/gbe/evx187
GL_GS5SSN	Physeter catodon	KLKB1	Other	Full	No	10.1093/gbe/evx187
GL_I1HS4Z	Physeter catodon	CPB1	Other	Full	Physeter	10.1093/gbe/evx187
GL_JKLYLE	Physeter catodon	F12	Other	Full	No	10.1093/gbe/evx187
GL_K2D4PX	Physeter catodon	MASP2	Other	Full	Physeter	10.1093/gbe/evx187