Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| CPA2 carboxypeptidase A2 | Homo sapiens | 11 | protein-coding | CPO , CPA6 , CPA3 , CPB1 , CPB2 , CPA5 , CPA1 , CPA4 | 3.4.17.15 | 600688 |
Summary
Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008]
GeneOntology
Gene Loss events - CPA2 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_4GNOS6 | Physeter catodon | Artiodactyla | Other | Full | No | 10.1093/gbe/evx187 |
| GL_XJYVCM | Balaena mysticetus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.celrep.2014.12.008 |