Gene Loss

Publication Details

Identifier: JB_QCAW4Q

Curator: M. Lopes-Marques

Title:

The Novel Evolution of the Sperm Whale Genome.

Abstract:

The sperm whale, made famous by Moby Dick, is one of the most fascinating of all ocean-dwelling species given their unique life history, novel physiological adaptations to hunting squid at extreme ocean depths, and their position as one of the earliest branching toothed whales (Odontoceti). We assembled the sperm whale (Physeter macrocephalus) genome and resequenced individuals from multiple ocean basins to identify new candidate genes for adaptation to an aquatic environment and infer demographic history. Genes crucial for skin integrity appeared to be particularly important in both the sperm whale and other cetaceans. We also find sperm whales experienced a steep population decline during the early Pleistocene epoch. These genomic data add new comparative insight into the evolution of whales.

Last update:

20-08-2024

Associated Glosses (19 results)

GlossID	Species	Symbol	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_K6OPOF	Physeter catodon	DPEP2	Other	Full	Physeter	10.1093/gbe/evx187
GL_SAQUEG	Physeter catodon	MMP12	Other	Full	No	10.1093/gbe/evx187
GL_SV5NHR	Physeter catodon	CAPN12	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evx187
GL_V0E0UZ	Physeter catodon	MMP7	LOF (frameshift, premature stop, ss)	Full	Physeter	10.1093/gbe/evx187
GL_VLG4OO	Physeter catodon	CPA3	Other	Full	No	10.1093/gbe/evx187
GL_VLIR8U	Physeter catodon	CPO	Other	Full	No	10.1093/gbe/evx187
GL_VXKBPZ	Physeter catodon	TMPRSS11F	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evx187
GL_XWHIKO	Physeter catodon	TPSAB1	Other	Full	No	10.1093/gbe/evx187
GL_Z54Y7P	Physeter catodon	PRSS33	Other	Full	No	10.1093/gbe/evx187