Ψ CPB1 - Physeter catodon

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_I1HS4Z Physeter catodon Other Full Yes Multiple individual SRA XM_024131886.1

Statements

Type Excerpt DOI
Methodology & Validation "To further ensure that assembly artifacts are not mistaken for gene losses, we used the Trace Archive Nucleotide BLAST to search inside RNA-Seq sets SRX220358, SRX220357, SRX220356, SRX220355, SRX220354, SRX220353, SRX220352, SRX220351 and SRX220350." 10.1093/gbe/evx187
Phenotypic "A loss of several proteases in cetaceans suggests a trend towards a milder inflammatory response relevant to Peto’s paradox: A theory postulated to explain the lower relative incidence of cancer in large mammals (CaulinandMaley2011)." 10.1093/gbe/evx187

Curator Observations

Sperm whale specific gene loss. The authors do not describe the gene loss mechanism but specify that this gene is lost see figure 1. See supplementary material for more details.