Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| CPB1 carboxypeptidase B1 | CPB , PASP , PCPB | Homo sapiens | 11 | protein-coding | CPO , CPA6 , CPA3 , CPB2 , CPA5 , CPA1 , CPA4 , CPA2 | 3.4.17.2 | 114852 |
Summary
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
GeneOntology
Gene Loss events - CPB1 (1 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_I1HS4Z | Physeter catodon | Artiodactyla | Other | Full | Physeter | 10.1093/gbe/evx187 |