Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| TMPRSS11B transmembrane serine protease 11B | HATL5 | Homo sapiens | 11 | protein-coding | TMPRSS4 , HPN , TMPRSS9 , TMPRSS6 , TMPRSS11E , TMPRSS11F , TMPRSS11D , TMPRSS11A , ST14 , TMPRSS7 , TMPRSS5 , TMPRSS15 , PRSS8 , CFI , TMPRSS3 , TMPRSS2 , TMPRSS13 , KLKB1 , F11 , PRSS51 , PRSS55 , PRSS41 , PRSS22 , PRSS27 , TMPRSS12 , PRSS50 |
Summary
Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
GeneOntology
Gene Loss events - TMPRSS11B (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_276009 | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/gbe/evx187 |
| GL_EKBCSB | Balaena mysticetus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.celrep.2014.12.008 |