Ψ TMPRSS11B - Balaena mysticetus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_EKBCSB | Balaena mysticetus | LOF (frameshift, premature stop, ss) | Full | No | Genomic & Transcriptomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "(...) related serine proteases F7, TMPRSS11F and TMPRSS11B are pseudogenes in bowhead and minke whales, but seem to be functional genes in dolphins." | 10.1016/j.celrep.2014.12.008 |
| Phenotypic | "These changes suggest that the mammalian potential for clotting and blood pressure are excessive in an aquatic environment, and these systems had to be modulated through the loss of proteases implicated in related proteolytic cascades." | 10.1016/j.celrep.2014.12.008 |
Curator Observations
See supplementary material for details.