Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| AMZ2 archaelysin family metallopeptidase 2 | Homo sapiens | 11 | protein-coding | 3.-.-.- | 615169 |
Summary
The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
GeneOntology
Gene Loss events - AMZ2 (1 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_8ND2IM | Physeter catodon | Artiodactyla | Other | Full | Physeter | 10.1093/gbe/evx187 |