Gene Loss

Publication Details

Identifier: JB_NAIFSC

Curator: M. Lopes-Marques

Title:

Increased rate of hair keratin gene loss in the cetacean lineage.

Abstract:

Hair represents an evolutionary innovation that appeared early on mammalian evolutionary history, and presumably contributed significantly to the rapid radiation of the group. An interesting event in hair evolution has been its secondary loss in some mammalian groups, such as cetaceans, whose hairless phenotype appears to be an adaptive response to better meet the environmental conditions. To determine whether different repertoire of keratin genes among mammals can potentially explain the phenotypic hair features of different lineages, we characterized the type I and II clusters of alpha keratins from eight mammalian species, including the hairless dolphin and minke whale representing the order Cetacea.

Last update:

01-09-2024

Associated Glosses (28 results)

GlossID	Species	Symbol	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_0LK1DO	Mus musculus	KRT3	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_0MKCQX	Balaenoptera acutorostrata	KRT31	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_6XXDNF	Tursiops truncatus	KRT86	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_A7DMGS	Equus caballus	KRT74	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_DNQV0U	Tursiops truncatus	KRT31	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_JJHPCQ	Tursiops truncatus	KRT82	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_JL0B5W	Tursiops truncatus	KRT38	Gene deletion	Full	No	10.1186/1471-2164-15-869
GL_K7MXXG	Tursiops truncatus	KRT37	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_KY51RH	Balaenoptera acutorostrata	KRT32	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_LNKYUR	Tursiops truncatus	KRT9	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869