Gene Loss

Publication Details

Identifier: JB_NAIFSC

Curator: M. Lopes-Marques

Title:

Increased rate of hair keratin gene loss in the cetacean lineage.

Abstract:

Hair represents an evolutionary innovation that appeared early on mammalian evolutionary history, and presumably contributed significantly to the rapid radiation of the group. An interesting event in hair evolution has been its secondary loss in some mammalian groups, such as cetaceans, whose hairless phenotype appears to be an adaptive response to better meet the environmental conditions. To determine whether different repertoire of keratin genes among mammals can potentially explain the phenotypic hair features of different lineages, we characterized the type I and II clusters of alpha keratins from eight mammalian species, including the hairless dolphin and minke whale representing the order Cetacea.

Last update:

01-09-2024

Associated Glosses (28 results)

GlossID	Species	Symbol	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_M1COOX	Balaenoptera acutorostrata	KRT38	Gene deletion	Full	No	10.1186/1471-2164-15-869
GL_NF4YEY	Tursiops truncatus	KRT79	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_OCARPZ	Balaenoptera acutorostrata	KRT83	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_OT1NFW	Balaenoptera acutorostrata	KRT82	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_QAI0KJ	Balaenoptera acutorostrata	KRT9	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_QFYFE9	Myotis lucifugus	KRT9	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_QPHYDG	Balaenoptera acutorostrata	KRT40	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_R547WP	Balaenoptera acutorostrata	KRT37	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_S3SQTF	Equus caballus	KRT9	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_TKXF9G	Balaenoptera acutorostrata	KRT75	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869