Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KRT74 keratin 74 | ADWH , ECTD7 , HTSS2 , HYPT3 , KRT5C , K6IRS4 , KRT6IRS4 | Homo sapiens | 9 | protein-coding | KRT8 , KRT6C , KRT6B , KRT6A , KRT80 , KRT71 , KRT72 , KRT73 , KRT77 , KRT78 , KRT4 , KRT79 , KRT76 , KRT3 , KRT2 , KRT1 , KRT75 , KRT5 , KRT85 , KRT86 , KRT81 , KRT83 , KRT84 , KRT82 , KRT7 | 608248 |
Summary
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This protein belongs to a family of keratins that are specifically expressed in the inner root sheath of hair follicles.[provided by RefSeq, Jun 2009]
GeneOntology
Gene Loss events - KRT74 (9 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_A7DMGS | Equus caballus | Perissodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
| GL_CDRNCX | Neophocaena asiaeorientalis asiaeorientalis | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_FV9V5K | Balaena mysticetus | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_HMOITS | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_PTZAS0 | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_RITPY6 | Physeter catodon | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_W3DDXR | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
| GL_XUFMV1 | Trichechus manatus latirostris | Sirenia | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_YZKA1O | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |