Reference Gene
Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
---|---|---|---|---|---|---|---|
KRT82 keratin 82 | HB2 , Hb-2 , KRTHB2 | Homo sapiens | 9 | protein-coding | KRT8 , KRT6C , KRT6B , KRT6A , KRT80 , KRT74 , KRT71 , KRT72 , KRT73 , KRT77 , KRT78 , KRT4 , KRT79 , KRT76 , KRT3 , KRT2 , KRT1 , KRT75 , KRT5 , KRT85 , KRT86 , KRT81 , KRT83 , KRT84 , KRT7 | 601078 |
Summary
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin. [provided by RefSeq, Jul 2008]
GeneOntology
Gene Loss events - KRT82 (9 results)
GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
---|---|---|---|---|---|---|
GL_AVHIPA | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
GL_BUD2ZV | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
GL_EY6DRG | Physeter catodon | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
GL_JJHPCQ | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
GL_OT1NFW | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
GL_RHXYUE | Balaena mysticetus | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
GL_VDEUW0 | Tursiops truncatus | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
GL_W6MCA4 | Neophocaena asiaeorientalis asiaeorientalis | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
GL_ZAVMJU | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |