Gene Loss

Publication Details

Identifier: JB_NAIFSC

Curator: M. Lopes-Marques

Title:

Increased rate of hair keratin gene loss in the cetacean lineage.

Abstract:

Hair represents an evolutionary innovation that appeared early on mammalian evolutionary history, and presumably contributed significantly to the rapid radiation of the group. An interesting event in hair evolution has been its secondary loss in some mammalian groups, such as cetaceans, whose hairless phenotype appears to be an adaptive response to better meet the environmental conditions. To determine whether different repertoire of keratin genes among mammals can potentially explain the phenotypic hair features of different lineages, we characterized the type I and II clusters of alpha keratins from eight mammalian species, including the hairless dolphin and minke whale representing the order Cetacea.

Last update:

01-09-2024

Associated Glosses (28 results)

GlossID	Species	Symbol	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_TVILNX	Balaenoptera acutorostrata	KRT35	Gene deletion	Full	No	10.1186/1471-2164-15-869
GL_UWQPC5	Balaenoptera acutorostrata	KRT33A	Gene deletion	Full	No	10.1186/1471-2164-15-869
GL_VCWAUF	Balaenoptera acutorostrata	KRT34	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_W3DDXR	Balaenoptera acutorostrata	KRT74	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_WHU5MX	Balaenoptera acutorostrata	KRT39	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_WQCG4R	Balaenoptera acutorostrata	KRT33B	Gene deletion	Full	No	10.1186/1471-2164-15-869
GL_XF7ORF	Balaenoptera acutorostrata	KRT79	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869
GL_XGO4QT	Tursiops truncatus	KRT83	LOF (frameshift, premature stop, ss)	Full	No	10.1186/1471-2164-15-869