Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KRT86 keratin 86 | HB6 , Hb1 , K86 , MNX , KRTHB1 , KRTHB6 | Homo sapiens | 11 | protein-coding | KRT8 , KRT6C , KRT6B , KRT6A , KRT80 , KRT74 , KRT71 , KRT72 , KRT73 , KRT77 , KRT78 , KRT4 , KRT79 , KRT76 , KRT3 , KRT2 , KRT1 , KRT75 , KRT5 , KRT85 , KRT81 , KRT83 , KRT84 , KRT82 , KRT7 | 601928 |
Summary
This gene encodes a type II keratin protein, which heterodimerizes with type I keratins to form hair and nails. This gene is present in a cluster of related genes and pseudogenes on chromosome 12. Mutations in this gene have been observed in patients with the hair disease monilethrix. [provided by RefSeq, Feb 2016]
GeneOntology
Gene Loss events - KRT86 (3 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_6XXDNF | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
| GL_FEFL8R | Ursus maritimus | Carnivora | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_GHRLZI | Vicugna pacos | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |