Ψ KRT86 - Vicugna pacos

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_GHRLZI Vicugna pacos Gene deletion Full No Genomic & Synteny maps

Statements

Type Excerpt DOI
Functional "Hair follicle-specific keratin genes consisted of 9 hair follicle-specific epithelial keratin genes (K71-K75, K25-K28) and 17 hair keratins (K31-K40, K81-K86) expressed in hair follicle and hair which could directly affect hair growth." 10.1186/s12983-017-0225-x
Methodology & Validation "We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] [Using the putative α-keratin cow genes as query,] the orthologous α-keratin genes were also scanned from the genome of [marine mammals'] terrestrial relatives, such as [...] alpaca (Vicugna pacos, coverage 22×, Vicugna_pacos-2.0.1, NCBI)." 10.1186/s12983-017-0225-x
Other "However, some genes within one specie grouped together rather than with the members of the same family in other species, such as among the genes of K31, K33A, K33B and K34 in type I, as well as the K6A, K6B, K6C, K81, K83, K87 and K86 in the type II." 10.1186/s12983-017-0225-x

Curator Observations

The authors named the keratins according to the human nomenclature. Gene not found in genomic maps-gene deletion (Fig1).