Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| MTNR1B melatonin receptor 1B | MT2 , FGQTL2 , MEL-1B-R | Homo sapiens | 4 | MNTR1A | 600804 |
Summary
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
Gene Loss events - MTNR1B (62 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_ZVASSZ | Delphinapterus leucas | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.3390/genes10020121 |
| GL_ZZ4ZCK | Choloepus hoffmanni | Pilosa | LOF (frameshift, premature stop, ss) | Full | Choloepus | 10.1007/s00239-021-10025-1 |