Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
MTNR1B melatonin receptor 1B MT2 , FGQTL2 , MEL-1B-R Homo sapiens 4 MNTR1A 600804

Summary

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

Gene Loss events - MTNR1B (62 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_RIMNAE Phyllostomus discolor Chiroptera LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_S55LYC Monodon monoceros Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_S6TK3T Talpa occidentalis Eulipotyphla Exon(s) deletion Full No 10.1007/s00239-021-10025-1
GL_TKRIVM Mirounga leonina Carnivora LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_USPVYW Phocoena sinus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_UUZA5A Chaetophractus vellerosus Cingulata LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_VNBCEB Tachyglossus aculeatus Monotremata LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_VSBWHR Ursus arctos horribilis Carnivora Exon(s) deletion Full Ursus 10.1007/s00239-021-10025-1
GL_WKXCHL Canis lupus dingo Carnivora LOF (frameshift, premature stop, ss) Full Canis lupus 10.1007/s00239-021-10025-1
GL_XXHOXK Chrysochloris asiatica Afrosoricida LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1