Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
MTNR1B melatonin receptor 1B MT2 , FGQTL2 , MEL-1B-R Homo sapiens 4 MNTR1A 600804

Summary

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

Gene Loss events - MTNR1B (62 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_MKLGPO Galeopterus variegatus Dermoptera LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_MX5GTH Manis javanica Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-021-10025-1
GL_MX98GK Cricetulus griseus Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_N4VSK3 Leptonychotes weddellii Carnivora LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_OZY6QU Suricata suricatta Carnivora LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_P2GVSL Tamandua tetradactyla Pilosa LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_PW1AXA Sarcophilus harrisii Dasyuromorphia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_QRIXCX Vombatus ursinus Diprotodontia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_QTCRD0 Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_RHHZBS Neophocaena asiaeorientalis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121