Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
AWAT2 acyl-CoA wax alcohol acyltransferase 2 WS , DC4 , ARAT , MFAT , DGAT2L4 Homo sapiens 8 DGAT2L6, DGAT2, MOGAT3, MOGAT2, MOGAT1, AWAT1 2.3.1.75 , 2.3.1.76 300925

Summary

This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]

GeneOntology

Gene Loss events - AWAT2 (16 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_0LE2VX Manis javanica Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-023-10118-z
GL_8JWURN Lipotes vexillifer Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_9UVZOR Manis crassicaudata Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-023-10118-z
GL_AAC5VE Manis pentadactyla Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-023-10118-z
GL_EZFDZ7 Balaena mysticetus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_EZG6QB Orcinus orca Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_FXMSOB Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_JZ5BYY Balaenoptera bonaerensis Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_LDKJJR Tursiops truncatus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068
GL_LI8CKQ Loxodonta africana Proboscidea LOF (frameshift, premature stop, ss) Full No 10.1093/molbev/msz068