Ψ AWAT2 - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_FXMSOB | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | No | Multiple individual SRA | XM_007119597.2 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Regarding P. catodon, Awat2 gene annotation revealed a premature stop codon in exon 3; given that the active site of this enzyme (HPHG) is located in exon 4 (Kawelke and Feussner 2015), it is reasonable to argue that Awat2 is pseudogenized in this species." | 10.1093/molbev/msz068 |
| Timing of Loss | "In contrast, the mutational events identified in Awat2 did not allow definite validation of pseudogenization in Cetacea." | 10.1093/molbev/msz068 |