Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| GSDMA gasdermin A | GSDM , FKSG9 , GSDM1 | Homo sapiens | 14 | GSDMD GSDMC GSDMB PJVK | 611218 |
Summary
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Involved in apoptotic process. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
GeneOntology
Gene Loss events - GSDMA (12 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_0MLL6N | Balaenoptera acutorostrata | Artiodactyla | Exon(s) deletion | Full | Cetacea | 10.1038/s41467-018-03667-1 |
| GL_5W933N | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-017-17782-4 |
| GL_ASKSUT | Physeter catodon | Artiodactyla | Exon(s) deletion | Full | Cetacea | 10.1038/s41467-018-03667-1 |
| GL_AWF07F | Tursiops truncatus | Artiodactyla | Gene deletion | Full | No | 10.1038/s41598-017-17782-4 |
| GL_CUM77K | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1038/s41598-017-17782-4 |
| GL_EZOGNH | Orcinus orca | Artiodactyla | Exon(s) deletion | Full | Cetacea | 10.1038/s41467-018-03667-1 |
| GL_MYVVYG | Tursiops truncatus | Artiodactyla | Exon(s) deletion | Full | Cetacea | 10.1038/s41467-018-03667-1 |
| GL_NBWWKO | Manis pentadactyla | Pholidota | Exon(s) deletion | Full | Manis | 10.1007/s00239-023-10118-z |
| GL_Q32ZSQ | Manis javanica | Pholidota | Exon(s) deletion | Full | Manis | 10.1007/s00239-023-10118-z |
| GL_Q6EWTH | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1038/s41598-017-17782-4 |