Ψ GSDMA - Manis javanica
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_Q32ZSQ | Manis javanica | Exon(s) deletion | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Timing of Loss | "Manual curation of the putatively pseudogenized Gsdma in M. pentadactyla unraveled two missing exons, as observed in M. javanica, in addition to the loss of a splicing site and a single-nucleotide deletion, both in exon 8, confirming the predicted coding status" | 10.1007/s00239-023-10118-z |
| Phenotypic | "Gsdma is specifically expressed in human epidermis, hair follicles, and sebaceous glands and was recently shown to be required for epidermal cornification and skin regeneration" | 10.1007/s00239-023-10118-z |