Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| TAS1R1 taste 1 receptor member 1 | TR1 , T1R1 , GM148 , GPR70 | Homo sapiens | 7 | protein-coding | GPRC6A , TAS1R2 , TAS1R3 , CASR | 606225 |
Summary
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
GeneOntology
Gene Loss events - TAS1R1 (16 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_NVYXIP | Ailuropoda melanoleuca | Carnivora | LOF (frameshift, premature stop, ss) | Full | No | 10.1007/s00114-012-0939-8 |
| GL_RLTQ47 | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1073/pnas.1118360109 |
| GL_U8CHMS | Otaria byronia | Carnivora | LOF (frameshift, premature stop, ss) | Full | Otariidae | 10.1007/s00114-012-0939-8 |
| GL_V1TW1L | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1186/s12862-014-0218-8 |
| GL_WAXIQA | Zalophus californianus | Carnivora | LOF (frameshift, premature stop, ss) | Full | No | 10.1073/pnas.1118360109 |
| GL_Y4DTNF | Balaenoptera omurai | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1186/s12862-014-0218-8 |