Ψ TAS1R1 - Ailuropoda melanoleuca
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_NVYXIP | Ailuropoda melanoleuca | LOF (frameshift, premature stop, ss) | Full | No | PCR & Sanger Sequencing Single | XM_034671154.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "The pseudogenizing mutations observed in the pinnipeds included a 4-bp frameshift insertion (positions 188–191; Fig.1) in four phocids (spotted seal, harbor seal, Caspian seal, and northern elephant seal), a 1-bp frameshift deletion (position 61) and a nonsense substitution (position 248) in one phocid (northern elephant seal), and a nonsense substitution (position 61) in two otariids (Australian sea lion and South American sea lion). A 2-bp frame-shift insertion previously reported from the giant panda (Li et al. 2010; Zhao et al. 2010) was confirmed (positions 297–298). Each of these mutations introduced a premature stop codon." | 10.1007/s00114-012-0939-8 |
| Other | "Partial DNA sequences of Tas1r1 exon 3 were newly determined for six pinnipeds and six other carnivorans. These sequences have been deposited in the DDBJ/EMBL/GenBank databases with accession numbers AB697513–AB697524." | 10.1007/s00114-012-0939-8 |
Curator Observations
An independent frameshift mutation in giant panda that had been reported in previous publications was confirmed.