Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
TAS1R1 taste 1 receptor member 1 TR1 , T1R1 , GM148 , GPR70 Homo sapiens 7 protein-coding GPRC6A , TAS1R2 , TAS1R3 , CASR 606225

Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

GeneOntology

Gene Loss events - TAS1R1 (16 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_6T1KMH Neophoca cinerea Carnivora LOF (frameshift, premature stop, ss) Full Otariidae 10.1007/s00114-012-0939-8
GL_BKH8YM Phoca largha Carnivora LOF (frameshift, premature stop, ss) Full Phocidae 10.1007/s00114-012-0939-8
GL_DT8ZQR Sousa chinensis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1186/s12862-014-0218-8
GL_ED2XZ2 Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1186/s12862-014-0218-8
GL_GYHAA9 Lipotes vexillifer Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1186/s12862-014-0218-8
GL_HTY3BB Phoca vitulina Carnivora LOF (frameshift, premature stop, ss) Full Phocidae 10.1007/s00114-012-0939-8
GL_JDUZET Pusa caspica Carnivora LOF (frameshift, premature stop, ss) Full Phocidae 10.1007/s00114-012-0939-8
GL_JFEHB1 Neophocaena phocaenoides Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1186/s12862-014-0218-8
GL_KAPWFZ Mirounga angustirostris Carnivora LOF (frameshift, premature stop, ss) Full Phocidae 10.1007/s00114-012-0939-8
GL_NS38RZ Kogia sima Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1186/s12862-014-0218-8