Ψ TAS1R1 - Tursiops truncatus
Reference Gene:
Job_ID:
Curator:
GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
---|---|---|---|---|---|---|
GL_V1TW1L | Tursiops truncatus | LOF (frameshift, premature stop, ss) | Full | Yes | PCR & Sanger Sequencing Single | XM_033844031.1 |
Statements
Type | Excerpt | DOI |
---|---|---|
Mutation Description | "Based on sequence alignments against cow (Bos taurus) homologues, we identified multiple ORF-disrupting indels and premature stop codons in Tas1r1, Tas1r2, Pkd2l1 and in ten Tas2rs scattered among cetacean branches." | 10.1186/s12862-014-0218-8 |
Timing of Loss | "For Tas1r1, we identified a premature stop codon shared by all cetaceans, a 5 bp deletion shared by all toothed whales and a 17 bp deletion in two baleen whales (Additional file 3: Figure S2)." | 10.1186/s12862-014-0218-8 |
Phenotypic | "Considering that both Tas1r1 and Tas1r2 had been identified as pseudogenes, we speculated that the umami and sweet tastes had been lost in the cetaceans." | 10.1186/s12862-014-0218-8 |
Other | "SEE "Additional file 3: Figures S1-S11. Indels and premature stop codons in Pkdl21, Tas1r1, Tas1r2, Tas2r1-3, Tas2r5, Tas2r16, Tas2r38-39, and Tas2r60." | 10.1186/s12862-014-0218-8 |
Curator Observations
Isolated sequences have been deposited by authors in GenBank [GenBank: KJ524713-KJ524837].
Related Glosses
GL_ID | Symbol | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
---|---|---|---|---|---|---|---|
GL_RLTQ47 | TAS1R1 | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1073/pnas.1118360109 |
GL_UZLRF1 | TAS1R1 | Tursiops truncatus | Artiodactyla | Other | Full | No | 10.1038/s41467-018-03667-1 |
GL_Z6LPE1 | TAS1R1 | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1186/s40851-014-0002-z |