Gene Loss

GlossID	Species	Gene Loss Mechanism	Loss Type	Lineage Specific	Evidence	Accession Nr.
GL_WAXIQA	Zalophus californianus	LOF (frameshift, premature stop, ss)	Full	No	PCR & Sanger Sequencing Single	XM_027607243.2

Type	Excerpt	DOI
Functional	"Mammalian sweet taste is primarily mediated by the type 1 taste receptor Tas1r2/Tas1r3, whereas Tas1r1/Tas1r3 act as the principal umami taste receptor."	10.1073/pnas.1118360109
Mutation Description	"By aligning with the dog Tas1r1 sequence, we found that the sea lion Tas1r1 has a 1-bp deletion in exon 2 between 53 and 54 bp (Fig. 4A and SI Appendix, Fig. S8A), and an 11-bp deletion in exon 6 between 302 and 303 bp (Fig. 4A and SI Appendix, Fig. S8B). (...). As was the case for Tas1r2, sea lion Tas1r1 and Tas1r3 are also pseudogenes."	10.1073/pnas.1118360109