Ψ CAPN12 - Balaena mysticetus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_MQPVWW | Balaena mysticetus | LOF (frameshift, premature stop, ss) | Full | No | Genomic & Transcriptomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "(...) CAPN12, a cysteine protease preferentially expressed at the cortex of the hair follicle25, has been lost in bowhead and minke whales (Supplemental Data File 1)." | 10.1016/j.celrep.2014.12.008 |
| Phenotypic | "(...), some of the differential characteristics of cetacean skin, like their parakeratotic stratum corneum with incomplete keratinization or its renewal through flaking rather than desquamation, might be related to the loss of several proteases." | 10.1016/j.celrep.2014.12.008 |
Curator Observations
See supplementary material for details.