| Functional |
"This protease is involved in dental enamel formation, and its pseudogenization in mammals, in concert with that of the metalloprotease MMP20, leads to amelogenesis imperfecta in mammals." |
10.1016/j.celrep.2014.12.008 |
| Mutation Description |
"KLK4 was pseudogenized through a frameshift mutation in a common ancestor to both whales,
but not in dolphins (Supplemental Data File 1)." |
10.1016/j.celrep.2014.12.008 |
| Phenotypic |
"Therefore, the loss of both KLK4 and MMP20 is likely to be related to the loss of teeth in the suborder Mysticeti." |
10.1016/j.celrep.2014.12.008 |