Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| GSDMC gasdermin C | MLZE | Homo sapiens | 21 | N/a | 608384 |
Summary
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within intestinal epithelial cell development. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Loss events - GSDMC (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_0SYFUX | Phataginus tricuspis | Pholidota | Other | Undetermined | No | 10.1007/s00239-023-10118-z |
| GL_2BWSUA | Manis crassicaudata | Pholidota | Other | Undetermined | No | 10.1007/s00239-023-10118-z |
| GL_N21JXJ | Manis javanica | Pholidota | LOF (frameshift, premature stop, ss) | Full | Manis | 10.1007/s00239-023-10118-z |
| GL_WC2VGR | Manis pentadactyla | Pholidota | LOF (frameshift, premature stop, ss) | Full | Manis | 10.1007/s00239-023-10118-z |