Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| TCHHL1 trichohyalin like 1 | THHL1 , S100A17 | Homo sapiens | 3 | N/a |
Summary
This gene belongs to the S100 fused-type protein (SFTP) gene family, and is located in a cluster of SFTP genes on chromosome 1q21. Several members of this family have been implicated in the development of complex skin disorders. This gene is evolutionarily conserved; its expression appears to be hair-specific and spatially restricted within the distal inner root sheath of the hair follicle. It thus may have an important role in hair morphogenesis. [provided by RefSeq, Aug 2013]
Gene Loss events - TCHHL1 (15 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_TH1NDQ | Manis javanica | Pholidota | LOF (frameshift, premature stop, ss) | Full | Manis | 10.1007/s00239-023-10118-z |
| GL_UAA3JE | Hippopotamus amphibius | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Hippopotamidae | 10.1016/j.cub.2021.02.057 |
| GL_UF33GW | Orcinus orca | Artiodactyla | Gene deletion | Full | Cetacea | 10.1016/j.cub.2021.02.057 |
| GL_WGMUAL | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1038/s41598-021-91863-3 |
| GL_ZZD6R5 | Physeter catodon | Artiodactyla | Gene deletion | Full | Cetacea | 10.1016/j.cub.2021.02.057 |