Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 PDHAL , SPGF70 Homo sapiens 1 protein-coding 1.2.4.1 179061

Summary

Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in pyruvate metabolic process. Located in mitochondrion and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

GeneOntology

Gene Loss events - PDHA2 (27 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_05EKTN Globicephala melas Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_0VGW2R Inia geoffrensis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_21MSTM Balaenoptera musculus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_3WBHS9 Lipotes vexillifer Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_68KJXB Phocoena phocoena Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_9RKFVY Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_AUU5NL Ziphius cavirostris Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_CQIUQJ Pontoporia blainvillei Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_CX5LMV Peponocephala electra Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062
GL_DFWLDH Sousa chinensis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.1016/j.cub.2021.05.062