| Mutation Description |
"Together, most of these metabolic steps are controlled by sperm-restricted gene orthologs, including (...) a converter of pyruvate to acetyl-CoA performed by the pyruvate dehydrogenase complex composed of several genes, including the sperm restricted Pdha2 (Figure 2) (...) We examined each gene ortholog sequence in various mammal species and found ORF-disrupting mutations or exon-loss events in most cetacean species (Figure 2; figshare link in Key resources table)." |
10.1016/j.cub.2021.05.062 |