Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| PGLYRP4 peptidoglycan recognition protein 4 | PGRPIB , SBBI67 , PGRP-Ibeta , PGLYRPIbeta | Homo sapiens | 11 | protein-coding | PGLYRP3 , PGLYRP1 , PGLYRP2 | 608198 |
Summary
Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
GeneOntology
Gene Loss events - PGLYRP4 (7 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_2F3LEZ | Orcinus orca | Artiodactyla | Gene deletion | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_D3TKZM | Tursiops truncatus | Artiodactyla | Gene deletion | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_DU1MUA | Balaenoptera acutorostrata | Artiodactyla | Gene deletion | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_FO6RWH | Elephas maximus indicus | Proboscidea | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-024-60099-2 |
| GL_JDKF8Z | Trichechus manatus | Sirenia | LOF (frameshift, premature stop, ss) | Full | Sirenia | 10.1038/s41598-024-60099-2 |
| GL_W5HRE8 | Dugong dugon | Sirenia | LOF (frameshift, premature stop, ss) | Full | Sirenia | 10.1038/s41598-024-60099-2 |
| GL_WVE9T1 | Physeter catodon | Artiodactyla | Gene deletion | Full | Cetacea | 10.1126/sciadv.aaw6671 |