Ψ PGLYRP4 - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_WVE9T1 | Physeter catodon | Gene deletion | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Fig. S19. Inactivating mutations in PGLYRP4. Visualization as in fig. S4. This gene is entirely deleted in all analyzed species, with shared deletion breakpoints, indicating an ancestral gene loss." | 10.1126/sciadv.aaw6671 |
| Other | "Furthermore, while mammals generally have four genes encoding peptidoglycan recognition proteins, which are receptors important for antimicrobial function and for maintaining a healthy gut microbiome, cetaceans have lost three of these four genes (PGLYRP1/3/4; figs. S17 to S19 and table S2)." | 10.1126/sciadv.aaw6671 |
Curator Observations
See reference supplementary material.