Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
ASMT acetylserotonin O-methyltransferase ASMTY , HIOMT , HIOMTY Homo sapiens 9 protein-coding 2.1.1.4 402500

Summary

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]

GeneOntology

Gene Loss events - ASMT (33 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_19TDCY Tolypeutes matacus Cingulata LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_1DU4PF Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_2UTTSQ Myrmecophaga tridactyla Pilosa LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_4GMSI0 Meriones unguiculatus Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_58LXHX Dipodomys ordii Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_58YTWG Manis javanica Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-021-10025-1
GL_6AAXPE Tursiops truncatus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_87VNDU Galeopterus variegatus Dermoptera LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_AXQTYW Choloepus didactylus Pilosa LOF (frameshift, premature stop, ss) Full Choloepus 10.1007/s00239-021-10025-1
GL_BHZHVB Phocoena sinus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1