Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
ASMT acetylserotonin O-methyltransferase ASMTY , HIOMT , HIOMTY Homo sapiens 9 protein-coding 2.1.1.4 402500

Summary

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]

GeneOntology

Gene Loss events - ASMT (33 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_DB9GKT Rhinopithecus roxellana Primates LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_DSH8TC Eschrichtius robustus Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_FBOFBE Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_FPC5XL Sousa chinensis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_FSHJBR Balaenoptera bonaerensis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_G7KHE4 Microtus ochrogaster Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_GUTFE2 Lagenorhynchus obliquidens Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_GW2VKL Manis pentadactyla Pholidota LOF (frameshift, premature stop, ss) Full Manis 10.1007/s00239-021-10025-1
GL_ILBVDL Mus musculus Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_KGMQN7 Choloepus hoffmanni Pilosa LOF (frameshift, premature stop, ss) Full Choloepus 10.1007/s00239-021-10025-1