Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
ASMT acetylserotonin O-methyltransferase ASMTY , HIOMT , HIOMTY Homo sapiens 9 protein-coding 2.1.1.4 402500

Summary

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]

GeneOntology

Gene Loss events - ASMT (33 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_KJ0Q98 Dasypus novemcinctus Cingulata Exon(s) deletion Full No 10.1007/s00239-021-10025-1
GL_MOHKL3 Myotis brandtii Chiroptera LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_MRBIHT Aotus nancymaae Primates LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_O6O3II Trichechus manatus Sirenia LOF (frameshift, premature stop, ss) Full 10.3390/genes10020121
GL_OIZMBQ Monodon monoceros Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_PKKP49 Delphinapterus leucas Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_QDSGBN Orcinus orca Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_U02MC6 Arvicanthis niloticus Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1
GL_UGO5C9 Neophocaena asiaeorientalis Artiodactyla LOF (frameshift, premature stop, ss) Full Cetacea 10.3390/genes10020121
GL_W6LPNG Mesocricetus auratus Rodentia LOF (frameshift, premature stop, ss) Full No 10.1007/s00239-021-10025-1