Ψ GSDMA - Manis crassicaudata
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_WYE0DR | Manis crassicaudata | Exon(s) deletion | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Further analysis highlighted a missing exon in M. crassicaudata (exon 6), out of the eleven that compose the gene" | 10.1007/s00239-023-10118-z |
| Phenotypic | "Gsdma is specifically expressed in human epidermis, hair follicles, and sebaceous glands and was recently shown to be required for epidermal cornification and skin regeneration" | 10.1007/s00239-023-10118-z |
Curator Observations
Further analysis highlighted a missing exon in M. crassicaudata (exon 6), out of the eleven that compose the gene