| Functional |
"(...) functions cyclic nucleotide-gated channel alpha 2 (CNGA2) and cyclic nucleotide-gated channel alpha 4 (CNGA 4) . These loci encode subunits of the olfactory cyclic nucleotide-gated (CNG) channel that is critical for depolarizing OR neurons and initiating action potentials that are sent to the brain (Michalakis et al.,2006; Nache et al., 2016)." |
10.1016/j.ympev.2017.01.020 |
| Mutation Description |
"For CNGA4, inactivating mutations occur in T. truncatus (1-bp frameshift deletion in exon 4), O. orca (4-bp frameshift deletion in exon 4), and Lipotes vexillifer (premature stop codon [TAC to TGA] and 1-
bp frameshift deletion in exon 4 , 2-bp frameshift insertion in exon 6) (Supplementary Alignment File3)." |
10.1016/j.ympev.2017.01.020 |
| Phenotypic |
"Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivatedin some odontocetes." |
10.1016/j.ympev.2017.01.020 |