Ψ ACP4 - Balaenoptera acutorostrata
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_ULLGHZ | Balaenoptera acutorostrata | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Seven of these genes are enamel specific (ACP4, AMBN, AMELX, AMTN, ENAM, KLK4, MMP20) and two are related to dentin/tooth formation (...)." | 10.1016/j.ympev.2022.107463 |
| Mutation Description | "Of the seven enamel genes, three (ACP4, KLK4, MMP20) were found to have inactivating mutations that are shared by all mysticetes. ACP4 has a 1-bp deletion in exon 4; KLK4 has a 1-bp deletion in exon 3; and MMP20 has a SINE insertion in exon 2." | 10.1016/j.ympev.2022.107463 |
| Timing of Loss | "34,62 MYA" | 10.1016/j.ympev.2022.107463 |
Curator Observations
See table 3 for details regarding mutations.
Related Glosses
| GL_ID | Symbol | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|---|
| GL_VBW3R1 | ACP4 | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41467-018-03667-1 |