Ψ DSPP - Eubalaena australis
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_QWO1IP | Eubalaena australis | LOF (frameshift, premature stop, ss) | Full | No | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "DSPP plays an essential role in the formation of dentin and the protease-processed products of DSPP comprise the largest component of non-collagenous proteins found in dentin (Yamakoshi and Simmer, 2018)." | 10.1016/j.ympev.2022.107463 |
| Mutation Description | "SPP exhibits two inactivating mutations that are shared by all four balaenids (1-bp insertion in exon 3, donor splice site mutation [AT] in intron 1) (Table 3). There is also a large deletion (e.g., 18.7 kb in Balaenoptera acutorostrata) that is present in all species of Plicogulae (Fig. 2B). This deletion includes the 5′ UTR, exon 1, intron 1, exon 2, intron 2, exon 3, intron 3, and most of exon 4. The remnants of exon 4 (including the stop codon) in different species of Plicogulae are only 390 to 585 bp in length." | 10.1016/j.ympev.2022.107463 |
| Timing of Loss | "19,94 MYA" | 10.1016/j.ympev.2022.107463 |
Curator Observations
See table 3 for details regarding mutations.