Ψ PDE6C - Balaenoptera borealis
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_PFTHVT | Balaenoptera borealis | LOF (frameshift, premature stop, ss) | Full | No | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Phenotypic | "The loss of function in GRK7 and other cone-specific genes identified here (OPN1LW, CNGB3, CNGA3, GNAT2, PDE6C) indicates that many more cetacean species have lost cone-mediated vision than previously known, including B. borealis, B. edeni, Caperea marginata, K. sima, Berardius bairdii, H. ampullatus, and many if not all species of Mesoplodon." | 10.1093/molbev/msaa070 |
| Other | "There was some evidence of shared inactivating mutations in a few genes, for example, B. borealis & B. edeni and M. densirostris, M. europaeus, and M. gingkodens in GRK7, and mutations in three sets of mysticetes that each do not form a monophyletic lineage in PDE6C and CNGA3." | 10.1093/molbev/msaa070 |
Curator Observations
Authors used Illumina genomic libraries and coverage to investigate coding status of the target genes (See table 1). Authors identified a 4nt deletion in exon 16, shared between Balaenoptera musculus, B. borealis, Eubalaena australis.