Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| PDE6C phosphodiesterase 6C | COD4 , ACHM5 , PDEA2 | Homo sapiens | 22 | protein-coding | PDE9A , PDE1A , PDE1B , PDE1C , PDE2A , PDE10A , PDE11A , PDE6B , PDE6A , PDE5A , PDE8A , PDE8B , PDE7A , PDE7B , PDE3A , PDE3B , PDE4C , PDE4A , PDE4D , PDE4B | 3.1.4.35 | 600827 |
Summary
This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4). [provided by RefSeq, Mar 2010]
GeneOntology
Gene Loss events - PDE6C (9 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_5UYFMO | Mesoplodon ginkgodens | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_BHEL6M | Balaenoptera musculus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_BWPJEG | Octodon degus | Rodentia | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_ETA0PO | Dasypus novemcinctus | Cingulata | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_HKQCDI | Caperea marginata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_NOKQUA | Eubalaena australis | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_PFTHVT | Balaenoptera borealis | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_WFCWJN | Balaenoptera edeni | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/molbev/msaa070 |
| GL_WVJKEM | Chrysochloris asiatica | Afrosoricida | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |