Ψ AWAT1 - Ceratotherium simum simum
Reference Gene:
Job_ID:
Curator:
GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
---|---|---|---|---|---|---|
GL_NFTK6J | Ceratotherium simum simum | LOF (frameshift, premature stop, ss) | Full | No | Single individual SRA | XM_004439879.2 |
Statements
Type | Excerpt | DOI |
---|---|---|
Mutation Description | "Notably, the presence of ORF disruptive mutations in Mogat3 in all analyzed species (fig. 3C), deleterious mutations in S. scrofa and C. s. simum Awat1 (fig. 3D) and in S. scrofa, L. africana and T. m. latirostris Awat2 (fig. 3D) and in both Dgat2l6 and Fabp9 from C. simum (fig. 3C and F). With the exception of a shared stop codon in the exon 6 of Awat1, all other mutations are not conserved between these species/lineages (fig. 3C and D; supplementary material 3, Supplementary Material online)." | 10.1093/molbev/msz068 |
Phenotypic | "In conclusion, our study supports convergent gene loss events in key molecular components responsible for skin sebum production in lineages reported to lack functioning SGs (Sebaceous Glands)." | 10.1093/molbev/msz068 |