Ψ TLR5 - Lipotes vexillifer

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_JXJRR0 Lipotes vexillifer LOF (frameshift, premature stop, ss) Full Yes Genomic 103072186

Statements

Type Excerpt DOI
Mutation Description "Indeed, we found that the second stop codon mutation is shared between all three river dolphin species (fig. 1A)." 10.1093/molbev/msaa058
Timing of Loss "Indeed, we found that the second stop codon mutation is shared between all three river dolphin species (fig. 1A). The presence of the same mutation in independently sequenced and assembled genomes makes it extremely unlikely that this mutation is a base error. Instead, this shared mutation strongly indicates that TLR5 was already lost in the common ancestor of the three river dolphin species." 10.1093/molbev/msaa058