Ψ EDA2R - Phataginus tricuspis

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_IYKZFO Phataginus tricuspis LOF (frameshift, premature stop, ss) Full No Single individual SRA

Statements

Type Excerpt DOI
Timing of Loss "For P. tricuspis, a 2-nucleotide insertion in exon 3 and a premature stop codon in exon 5 were retrieved, denoting an independent Eda2r loss across Asian and African pangolin lineage." 10.1007/s00239-023-10118-z
Phenotypic "In agreement, evidence of erosion was found in genes related with keratinocyte proliferation and stabilization (i.e., Slurp1) or hair development and mechanical strength (i.e., Edar2, Tchhl1)" 10.1007/s00239-023-10118-z