Ψ ELOVL3 - Balaenoptera acutorostrata

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_IWQHLH Balaenoptera acutorostrata LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA XM_007187279.2

Statements

Type Excerpt DOI
Mutation Description "Subsequent annotation of the collected genomic sequences revealed a trans-species conserved premature stop codon in exon 3, further validated by SRA searches (fig. 2C and supplementary material 2, Supplementary Material online). These results constitute a strong indication that Elovl3 is inactive in the analyzed species." 10.1093/molbev/msz068
Timing of Loss "Interestingly, the mutational pattern deduced in Dgat2l6, Mogat3, Awat1, Elovl3, and Fabp9 allowed the identification of conserved founding mutations common to all analyzed Cetacea (fig. 4). The sharing of mutations constitutes a strong indication of common pseudogenization events prior to the diversification of modern Cetacea lineages." 10.1093/molbev/msz068

Curator Observations

Single conserved premature stop codon in exon 3 in all cetaceans analyzed in this work.