Ψ ELOVL3 - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_HIDRFX | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_007126871.3 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Subsequent annotation of the collected genomic sequences revealed a trans-species conserved premature stop codon in exon 3, further validated by SRA searches (fig. 2C and supplementary material 2, Supplementary Material online). These results constitute a strong indication that Elovl3 is inactive in the analyzed species." | 10.1093/molbev/msz068 |
| Timing of Loss | "Interestingly, the mutational pattern deduced in Dgat2l6, Mogat3, Awat1, Elovl3, and Fabp9 allowed the identification of conserved founding mutations common to all analyzed Cetacea (fig. 4). The sharing of mutations constitutes a strong indication of common pseudogenization events prior to the diversification of modern Cetacea lineages." | 10.1093/molbev/msz068 |
Curator Observations
Single conserved premature stop codon in exon 3 in all cetaceans analyzed in this work.