Ψ UBE2N - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_H5MMSK | Physeter catodon | Other | Full | No | Genomic | XP_23977326.1; XP_28350815.1 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Methodology & Validation | "UBC domain HMM profiles searches, database domain validation, and manual curation revealed 39 UBE2 genes in the sperm whale genome (files in electronic supplementary at http://www.ias.ac.in/jgenet/), including 32 intact genes, one partial gene, and six pseudogenes." | 10.1007/s12041-021-01333-y |
| Phenotypic | "We speculate that an expansion (sperm whale vs human: 4:1) of UBE2N subfamily in sperm whale contributes to enhanced oxidative damage repair." | 10.1007/s12041-021-01333-y |
Curator Observations
UBE2N_2 and UBE2N_3 are mentioned as pseudogenes in Table S1. Details are not given regarding the mutations found except the loss of Motif 2 in UBE2N_3 (Figure 2). Two of the four UBE2N gene are considered pseudo.